The PANCE exam is a computer-based, timed test comprised of 300 multiple-choice questions assessing medical and surgical knowledge required to become a certified physician assistant. The PANCE exam is administered in 5 blocks of 60 questions each, with 60 minutes provided for the completion of each block. Exam questions fall into two categories: organ systems and diseases, disorders and medical assessments that relate to those systems; and knowledge and skills needed to confront those diseases, disorders and assessments. The PANCE exam is administered by computer year round at more than 200 Pearson VUE testing centers throughout the U.S.